Politis

Antibiotics After Sex to Prevent STIs: A Growing Practice Raises Concerns

Published January 20, 2026, 05:16
Antibiotics After Sex to Prevent STIs: A Growing Practice Raises Concerns

The practice of taking antibiotics after sexual intercourse, known as doxy-PEP, is gaining traction in European countries as a preventative measure against sexually transmitted infections (STIs) such as syphilis, chlamydia, and to a lesser extent, gonorrhea. This method, involving the intake of doxycycline within 24-72 hours post-sex, has demonstrated effectiveness in high-risk groups, such as men who have sex with men. However, the European Centre for Disease Prevention and Control (ECDC) warns of the risk of developing antibiotic resistance, which could compromise the treatment of other infections. The concern is particularly acute for gonorrhea, where increased rates of resistance are already being observed. The ECDC emphasizes that doxy-PEP should not be considered a quick fix and does not replace the use of condoms, regular STI testing, and comprehensive sexual health care. In Cyprus, where there are no official guidelines or data on the use of doxy-PEP, the ECDC's warning is particularly relevant, given the high use of antibiotics and the fragmented epidemiological picture of STIs. The lack of a comprehensive sexual health policy framework further complicates the situation. Doxy-PEP is not a vaccine or a permanent treatment, but a post-exposure prophylaxis. Its effectiveness has been primarily observed in groups frequently exposed to infection risk. The concern about antibiotic resistance extends beyond STIs, posing a serious threat to public health. Prophylactic antibiotic use can accelerate the development of resistance, rendering treatments less effective in the future.